Clinical Research & Findings

Clinical Research & Development Partner
Signing Ceremony of the MoU of Collaborative Studies between Usains Holding of Universiti Sains Malaysia and BioFact Life which was officiated and witnessed by YAB Tan Sri Dr. Koh Tsu Koon, Former Chief Minister of Penang, Malaysia 2007.

The following is a list of positive effects of cordyceps based on recent research and clinical findings :

Cordyceps improves respiratory function
Several scientific studies have demonstrated the benefits of cordyceps in alleviating the symptoms of several respiratory illnesses including chronic bronchitis and asthma (Reference 2, Chapter "Effects on the Respiratory System", pages 429-432). In a double-blind, placebo controlled study with 30 elderly volunteers, Cordyceps significantly improved the maximum amount of oxygen these people were able to assimilate (Reference 4).

Cordyceps increases cellular oxygen absorption by up to 40%
(Lou Y, Liao X, Lu Y. Cardiovascular pharmacological studies of ethanol extracts of Cordyceps mycelia and Cordyceps fermentation solution. Chinese Traditional and Herbal Drugs 1986;17(5):17-21,209-213) Chronic obstructive pulmonary diseases improvement of 40% after cordyceps supplement. (Wang WQ. J. Administration Traditional Chinese Med 1995;5 (supp;):24)

Cordyceps helps maintain cholesterol level
Four excellent studies have demonstrated that Cordyceps sinensis helps to lower total cholesterol by 10 to 21% and triglycerides by 9 to 26%. At the same time it helps to increase HDL-cholesterol ("good cholesterol") by 27 to 30% (Reference 1, Chapter "Effects on blood lipid metabolism and arteriosclerosis", pages 299 - 301).

Blood Cells Improves Blood Cell Viability & Function.
Genetic Promotes DNA Repair
Liver Protection Improves Liver Functions, helps with Hepatitis and Cirrhosis Sub chronicand chronic hepatitis on related
liver diseases are more prevalent than most people think. Liver is the living filter of the
human body, cleaning the blood and all other fluids of impurities. There is no way for you to survive,
much less feel healthy, without a functioning liver.

Research clinical trials on 33 patients with Hepatitis "B" and on another 8 patients with cirrhosis
taking Cordyceps supplement showed 71.9% improvement on "Thymol Turbidity Test"
and 78.6% improvement in "SGPT Test" both of these are enzyme test showing
improving functions of the liver. (Zhou LT, Yang YZ, Xu YM, Zhu QY, Zhu YR, Ge XY, Gao JD.
Short term curative effect of culturedCordyceps sinensis (Berk.) Sacc.
Mycelia in chronic hepatitis B.China J Chinese Materia Medica 1990;15(1):53-55)

Chronic kidney diseases improvement
Chronic kidney diseases improvement of 51% after only one month with cordyceps supplement.(Jiang JC, Gao YF. J Administration Traditional Chinese Med 1995;5(suppl):23-24)

Cordyceps reduces tumor size in cancer patients
Several clinical studies have been conducted in China and Japan with cancer patients (References 1 and 2). The studies were done with CSE (cordyceps sinensis mycelium) using a therapeutic dose of 6 grams per day (= 4 capsules twice daily). In one study with 50 lung cancer patients administered CSE in conjunction with chemotherapy, tumors reduced in size in 46% of patients. A study in cancer patients with various types of tumors found CSE (6 g/day for over 2 months) improved subjective symptoms in the majority of patients. White blood cell counts were maintained and tumor size was significantly reduced in about half of the patients. Researchers in Japan reported that CSE enhances the general reactivity of the immune system in individuals with cancer.

Cordyceps strengthens the immune system
Increases Natural Killer (NK) cell activity, develops more MUSCLE — Increases Power, builds better and younger cells.
Recharge the Protective Army of NK cells — Your body‘s ability to fight infections and tumors depends on the availability of Natural Killer (NK) Cells. These are essential first lines of defense for our body‘s protection mechanisms commonly known as the immune system. Several scientific studies of cordyceps have especially focused on Natural Killer (NK) cells and the effect of cordyceps on them and cancer formation. One such in-vitro study demonstrated cordyceps adding significant enhancement of NK cell activity in normal individuals as well as leukemia-stricken individuals. (Liu C, Lu S, Ji MR, Xie Y. effects of Cordyceps sinensis on in-vitro natural killer cells.
Chinese Integrated Traditional Western Med (Chung-Kuo Chung His I Chieh Ho Tsa Chih) 1992;12(5):267-269) showed that natural cordyceps enhanced the NK cell activity of normal patients by 74% and increased the NK activity of leukemia patients by 400% and similar improvements of NK cell activities was found in big melanoma cancer (Xu RH, Peng XE, Chen GZ, Chen GL. Effects of cordyceps sinensis on natural killer activity and colony formation of B16 melanoma. Chinese Med J 1992;105(2):97-101). The improvements in the immune system were so impressive that in the Journal of Alternative and Complementary Medicine 1998, Dr Zhu stated: " Because of the above profound influence on immune functions, natural Cordyceps products have been used in many clinical conditions in patients with altered immune functions."

Anti-aging : The first anti-aging supplement known to mankind
It is an anti-aging fighter with clinical research proof in controlled studies which showed that elderly patients suffering from fatigue and some senility-related symptoms reported reduced fatigue(92%), improvement in ability to withstand cold(89%) and less frequent dizzy spells(83%) after consuming cordyceps for 30 days. P (Cao A, Wen Y. J Applied Traditional Chinese Med 1993;1:32-33)").

Cordyceps protects against free radical damage
Several studies have shown that cordyceps sinensis protects against the damages caused by free radicals, and as such has powerful antioxidant properties (Reference 1, Chapter "Antisenescence and Oxygen-Free Radical Scavenging Activity").

Cordyceps reduces fatigue
Several studies with animals have demonstrated that cordyceps sinensis increases the cellular energy production and oxygen supply. A double-blind, placebo-controlled investigation showed a marked reduction in fatigue in elderly patients when they were given three grams of cordyceps daily. In another study, cordyceps sinensis reduced episodes of shortness of breath and reduced fatigue in patients suffering from chronic heart failure (Reference 1, Chapter "Improvement of physical performance and quality of life", pages 293 — 295).

Cordyceps improves stamina and athletic performance
Several studies with animals have shown that cordyceps sinensis increases the cellular energy production and oxygen uptake ( Reference 1, Chapter " Improvement of physical performance and quality of life", pages 293 — 295). A study with mice demonstrated their improved swimming capabilities after six weeks of cordyceps supplementation compared with a control group (Reference 3, page 260).

Cordyceps radically increases cellular energy
Cellular energy is also known scientifically as the ATP/IP ratio. Cordyceps has been clinically proven to increase cellular bioenergy by as much as 55% (Reported on XU C.F et al in ZHU J-S, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: Part I. J Alt Comp Med 1998;4(3):289-303.).

Cordyceps combats sexual dysfunction
Three separate Chinese double-blind and placebo-controlled studies with over 200 men with "reduced libido and other sexual problems" showed remarkably similar results. On average, 64% of the cordyceps-users reported significant improvement at the conclusion of the experimental period compared with 24% of the placebo group. In another double-blind, placebocontrolled study conducted with 21 elderly women with similar complaints, 90% reported improvements in their condition following the use of cordyceps compared with none in the control group (Reference 1).

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